Rapid development of 9 cerebral aneurysms in varicella-zoster virus vasculopathy

Neurology. 2014 Jun 10;82(23):2139-41. doi: 10.1212/WNL.0000000000000503. Epub 2014 May 14.

Abstract

A patient with zoster in multiple dermatomes, severe headache, and normal magnetic resonance angiography (MRA) and 4-vessel digital subtraction angiogram (DSA) developed 9 anterior circulation aneurysms 2 months later. Antiviral treatment resulted in clinical improvement, size reduction of most aneurysms, and complete resolution of the 2 largest aneurysms.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / pharmacology*
  • Antiviral Agents / administration & dosage
  • Antiviral Agents / pharmacology*
  • Disease Progression
  • Encephalitis, Varicella Zoster / cerebrospinal fluid
  • Encephalitis, Varicella Zoster / complications*
  • Encephalitis, Varicella Zoster / drug therapy
  • Female
  • Herpes Zoster / drug therapy
  • Herpes Zoster / pathology
  • Herpesvirus 3, Human / pathogenicity*
  • Humans
  • Intracranial Aneurysm / etiology*
  • Magnetic Resonance Imaging
  • Time Factors

Substances

  • Anti-Inflammatory Agents
  • Antiviral Agents