Current trends in the management of pulmonary hypertension associated with respiratory disease in institutions approved by the Japanese Respiratory Society

Respir Investig. 2014 May;52(3):167-72. doi: 10.1016/j.resinv.2013.11.003. Epub 2013 Dec 18.

Abstract

Background: Pulmonary hypertension (PH) often correlates with respiratory disease severity. Right heart catheterization (RHC) is recommended for the definitive diagnosis of PH associated with respiratory disease (R-PH). However, no previous studies have evaluated the perceived necessity for pulmonologists to use RHC for R-PH diagnosis, or the management of R-PH in Japan.

Methods: Questionnaires were mailed to 855 institutions, approved by the Japanese Respiratory Society. Questions included the prevalence and necessity of RHC and other methods in R-PH diagnosis, and current trends in the treatment of R-PH.

Results: Questionnaires were returned from 289 institutions (34%). Patients with R-PH were examined by pulmonologists in 89% of institutions; some pulmonologists performed echocardiography (15%) and some RHC (13%). Echocardiography was used to diagnose R-PH in 99% of institutions and RHC was used in 36%. RHC was considered in cases of suspected PH in 49% of institutions and prior to initiation of pulmonary arterial hypertension (PAH)-specific therapy in 57%. Of patients diagnosed with R-PH, 47% were treated with ambulatory oxygen therapy. Furthermore, 98 of 145 institutions used PAH-specific therapy to treat R-PH. Of the 1355 patients who underwent RHC as a part of PH evaluation, 29% were confirmed to have PH, and 8% had severe PH with a mean pulmonary arterial pressure of ≥35mmHg.

Conclusions: The current diagnostic and treatment modalities for R-PH in Japan were evaluated. Although few pulmonologists perform RHC for R-PH diagnosis in Japan, more than half consider using RHC for patients before initiating PAH-specific therapy.

Keywords: Chronic obstructive pulmonary disease; Pulmonary hypertension; Pulmonologist; Respiratory disease; Right heart catheterization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Academies and Institutes / statistics & numerical data
  • Arterial Pressure
  • Cardiac Catheterization / statistics & numerical data*
  • Disease Management*
  • Echocardiography / statistics & numerical data
  • Humans
  • Hypertension, Pulmonary / complications*
  • Hypertension, Pulmonary / diagnosis*
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / therapy
  • Japan
  • Oxygen Inhalation Therapy / statistics & numerical data
  • Pulmonary Artery / physiopathology
  • Pulmonary Medicine / organization & administration*
  • Respiratory Tract Diseases / complications*
  • Respiratory Tract Diseases / diagnosis
  • Severity of Illness Index
  • Societies, Medical / organization & administration*
  • Surveys and Questionnaires