Treatment of nocturnal enuresis: a placebo-controlled trial with piracetam, diphenylhydantoin and psychotherapy

Turk J Pediatr. 1989 Jul-Sep;31(3):215-20.

Abstract

The study population consisted of 100 children with nocturnal enuresis (NE) aged between six and 14 years, who had been randomly selected amongst the enuretic outpatients at the Ankara S.S.K. Children's Hospital. A placebo-controlled evaluation of piracetam, diphenylhydantoin and psychotherapy was carried out. At the end of the eighth week of the study, it was discovered that the therapeutic effects observed in the patients administered piracetam did not differ from those given the placebo. Therefore, we recommend that psychotherapy in association with a placebo be the first step in the treatment of NE children.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Child
  • Combined Modality Therapy
  • Enuresis / drug therapy*
  • Enuresis / therapy
  • Female
  • Humans
  • Male
  • Phenytoin / administration & dosage
  • Phenytoin / therapeutic use*
  • Piracetam / administration & dosage
  • Piracetam / therapeutic use*
  • Psychotherapy / standards*

Substances

  • Phenytoin
  • Piracetam