TGFβ/SMAD4 signalling is inhibited in tumour cells and infiltrating lymphocytes of a patient with colon cancer-associated dermatomyositis

J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2265-7. doi: 10.1111/jdv.12569. Epub 2014 May 23.

Authors

A Kasuya¹, T Hoshino¹, M Aoshima¹, K Tatsuno¹, T Fujiyama¹, Y Tokura¹

Affiliation

¹ Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

PMID: 24862343
DOI: 10.1111/jdv.12569

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adenocarcinoma / metabolism*
Adenocarcinoma / secondary
Aged
Colonic Neoplasms / metabolism*
Colonic Neoplasms / pathology
Dermatomyositis / metabolism*
Female
Humans
Lymphatic Metastasis
Lymphocytes / metabolism*
Paraneoplastic Syndromes / metabolism*
Signal Transduction
Smad4 Protein / metabolism*
Transcription Factors / metabolism
Transforming Growth Factor beta / metabolism*

Substances

SMAD4 protein, human
Smad4 Protein
TRIM33 protein, human
Transcription Factors
Transforming Growth Factor beta