Ibrutinib resistance in chronic lymphocytic leukemia

MeSH terms

• Adenine / analogs & derivatives
• Agammaglobulinaemia Tyrosine Kinase
• Drug Resistance, Neoplasm / genetics*
• Female
• Humans
• Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy
• Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
• Middle Aged
• Phosphorylation
• Piperidines
• Point Mutation*
• Protein-Tyrosine Kinases / antagonists & inhibitors*
• Protein-Tyrosine Kinases / chemistry
• Protein-Tyrosine Kinases / metabolism
• Pyrazoles / metabolism
• Pyrazoles / therapeutic use*
• Pyrimidines / metabolism
• Pyrimidines / therapeutic use*
• Receptors, Antigen, B-Cell / metabolism
• Recurrence
• Sequence Analysis, DNA