Antegrade continent enema procedures performed prior to starting school may improve functional stooling and quality of life

Pediatr Surg Int. 2014 Jul;30(7):715-22. doi: 10.1007/s00383-014-3520-z. Epub 2014 May 30.

Abstract

Purpose: A major research gap is determining the best age to perform an appendicostomy or cecostomy. This study hypothesizes that performance of appendicostomy/cecostomy prior to starting school (<6 years) would improve functional stooling and quality of life (QOL).

Methods: Patients who underwent appendicostomy/cecostomy for bowel management between 2003 and 2013 were retrospectively identified. Families were prospectively surveyed regarding current stooling habits (17 items) and a (7 item) pediatric QOL survey. Lower stooling survey scores represent better bowel control. Higher QOL scores indicated better quality. The primary outcome was to correlate age of appendicostomy/cecostomy to QOL score. Statistics were performed using paired, unpaired t tests, and Chi-square. p Values ≤0.05 were considered significant.

Results: 35 patients underwent placement of appendicostomy/cecostomy. Fourteen (40%) patients/families were prospectively contacted (<6, n = 6; >6, n = 8). Stooling scores (15.17 ± 1.35 vs. 22.25 ± 1.70; for <6 vs. >6 years old, p = 0.009) and continence scores (6.33 ± 1.45 vs. 11.13 ± 1.64; p = 0.06), at time of contacting families, were significantly better in those undergoing appendicostomy/cecostomy in the <6 group. Pre-procedure QOL scores for the two groups were similar (p = 0.89). Post-procedure QOL significantly increased to the good subcategory for both age groups; however improvement was significantly better in the <6 age group vs. ≥6 group: 6.33 ± 0.92 vs. 3.13 ± 0.91 points (p = 0.03). A secondary parent survey showed significantly more families wished an appendicostomy/cecostomy were done earlier in the >6 vs. <6 group (87.5 vs. 33%; p = 0.04).

Conclusion: Early placement of cecostomy or appendicostomy as part of a bowel management program may contribute to improved QOL and functional stooling.

MeSH terms

  • Child
  • Constipation / physiopathology
  • Constipation / psychology
  • Constipation / therapy*
  • Defecation / physiology*
  • Enema / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Quality of Life*
  • Retrospective Studies
  • Surveys and Questionnaires*
  • Time Factors
  • Treatment Outcome