Enhancing brain lesions after endovascular treatment of aneurysms

AJNR Am J Neuroradiol. 2014 Oct;35(10):1954-8. doi: 10.3174/ajnr.A3976. Epub 2014 May 29.

Abstract

Complications of endovascular therapy of aneurysms mainly include aneurysm rupture and thromboembolic events. The widespread use of MR imaging for follow-up of these patients revealed various nonvascular complications such as aseptic meningitis, hydrocephalus, and perianeurysmal brain edema. We present 7 patients from 5 different institutions that developed MR imaging-enhancing brain lesions after endovascular therapy of aneurysms, detected after a median time of 63 days. The number of lesions ranged from 4-46 (median of 10.5), sized 2-20 mm, and were mostly in the same vascular territory used for access. Three patients presented with symptoms attributable to these lesions. After a median follow-up of 21.5 months, the number of lesions increased in 2, was stable in 1, decreased in 3, and disappeared in 1. The imaging and clinical characteristics suggested a foreign body reaction. We could find no correlation to a specific device, but a possible source may be the generic hydrophilic coating.

MeSH terms

  • Adult
  • Brain / pathology*
  • Brain Diseases / etiology*
  • Embolization, Therapeutic / adverse effects
  • Endovascular Procedures / adverse effects*
  • Female
  • Humans
  • Hydrocephalus / etiology
  • Intracranial Aneurysm / surgery*
  • Intracranial Aneurysm / therapy
  • Male
  • Middle Aged