Aim: To review current data available on use of prostate specific antigen for screening healthy men for prostate cancer.
Methods: Literature was reviewed and the guidelines from, American cancer Society, American Urologic Association was reviewed.
Results: Current screening protocols lead to over diagnosis of prostate cancer. This often results in unnecessary biopsy procedures and treatments.
Conclusion: We must consider the benefit of screening and treatment with the harms of over diagnosis and over treatment. Newer imaging modalities like magnetic resonance imaging have to be evaluated further.
Keywords: Prostate cancer; Prostate-specific antigen; Screening.