Abstract
Three phthalocyanines (Pcs) conjugated with α-, β- and γ-cyclodextrins (CDs) were prepared and their application as photosensitizer (PS) agents was assessed by photophysical, photochemical and in vitro photobiological studies. The photoactivity of Pc-α-CD and Pc-γ-CD ensures their potential as PDT drugs against UM-UC-3 human bladder cancer cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line
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Cell Nucleus / chemistry
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Cell Nucleus / pathology
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Cell Survival / drug effects
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Cyclodextrins / chemistry*
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Humans
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Indoles / chemistry*
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Isoindoles
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Light
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Microscopy, Fluorescence
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Photochemotherapy
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Photosensitizing Agents / chemical synthesis*
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Photosensitizing Agents / therapeutic use
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Photosensitizing Agents / toxicity
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Urinary Bladder Neoplasms / drug therapy
Substances
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Cyclodextrins
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Indoles
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Isoindoles
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Photosensitizing Agents
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phthalocyanine