PDGFRB-rearranged T-lymphoblastic leukemia/lymphoma occurring with myeloid neoplasms: the missing link supporting a stem cell origin

Haematologica. 2014 Sep;99(9):e148-51. doi: 10.3324/haematol.2014.105452. Epub 2014 Jun 20.
No abstract available

Keywords: PDGFRB; T-lymphoblastic; leukemia; lymphoma; myeloid neoplasm.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Bone Marrow / metabolism
  • Bone Marrow / pathology
  • Gene Expression
  • Humans
  • Karyotype
  • Leukemia, Myeloid / complications
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / genetics*
  • Leukemia, Myeloid / pathology
  • Male
  • Middle Aged
  • Neoplastic Stem Cells / metabolism
  • Neoplastic Stem Cells / pathology*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Receptor, Platelet-Derived Growth Factor beta / genetics*
  • Receptor, Platelet-Derived Growth Factor beta / metabolism
  • Translocation, Genetic*

Substances

  • Receptor, Platelet-Derived Growth Factor beta