Abstract
In this review we examine the current understanding of how genetic deficits associated with neurodevelopmental disorders may impact synapse assembly. We then go on to discuss how the critical periods for these genetic deficits will shape the nature of future clinical interventions.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Child
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Developmental Disabilities / genetics
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Developmental Disabilities / metabolism*
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Humans
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Nerve Tissue Proteins / genetics
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Nerve Tissue Proteins / metabolism
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Neurogenesis / physiology
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Neuronal Plasticity / physiology*
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Synapses / genetics
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Synapses / metabolism*