High-throughput drug screening identifies compounds and molecular strategies for targeting proteasome inhibitor-resistant multiple myeloma

Leukemia. 2014 Nov;28(11):2263-7. doi: 10.1038/leu.2014.214. Epub 2014 Jul 9.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Boronic Acids / pharmacology*
  • Bortezomib
  • Drug Resistance, Neoplasm
  • Enzyme Inhibitors / pharmacology*
  • High-Throughput Screening Assays / methods*
  • Humans
  • Mice
  • Multiple Myeloma / drug therapy*
  • Multiple Myeloma / enzymology
  • Proteasome Endopeptidase Complex / metabolism*
  • Pyrazines / pharmacology*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Boronic Acids
  • Enzyme Inhibitors
  • Pyrazines
  • Bortezomib
  • Proteasome Endopeptidase Complex