Second hematologic malignancies in hairy cell leukemia: report of two patients with dynamic mutations in the BRAF gene

Leuk Lymphoma. 2015 Mar;56(3):823-5. doi: 10.3109/10428194.2014.939966. Epub 2014 Aug 20.

Authors

Kalman Filanovsky¹, Rinat Yacobi, Eliakim Vorst, Iris Barshack, Eva Ustaev, Edit Feldberg, Lev Shvidel

Affiliation

¹ Hematology Institute, Kaplan Medical Center , Rehovot , Israel.

PMID: 25029639
DOI: 10.3109/10428194.2014.939966

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antigens, CD20 / metabolism
Antineoplastic Agents / therapeutic use
Cladribine / therapeutic use*
DNA Mutational Analysis
Female
Hematologic Neoplasms / diagnosis*
Hematologic Neoplasms / metabolism
Humans
Immunohistochemistry
Leukemia, Hairy Cell / drug therapy*
Leukemia, Hairy Cell / genetics
Leukemia, Hairy Cell / metabolism
Lymphoma, Large B-Cell, Diffuse / diagnosis
Lymphoma, Large B-Cell, Diffuse / metabolism
Male
Middle Aged
Mutation*
Neoplasms, Second Primary / diagnosis*
Neoplasms, Second Primary / metabolism
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / metabolism
Proto-Oncogene Proteins B-raf / genetics*

Substances

Antigens, CD20
Antineoplastic Agents
Cladribine
BRAF protein, human
Proto-Oncogene Proteins B-raf