Standardization and quantification in PET/CT imaging: tracers beyond FDG

PET Clin. 2014 Jul;9(3):259-66. doi: 10.1016/j.cpet.2014.03.002. Epub 2014 May 6.

Abstract

Standardization of FDG PET-CT is becoming a reality, at least in centers that perform clinical trials. Non-FDG radiopharmaceuticals used with PET/CT are far from standard in clinical trials and in clinical use. This article only gives an example of different protocols and indications related to the availability of different radiopharmaceuticals. This scenario will be probably the reality in the near future in many centers throughout the world. Starting from the FDG experience, it will be easy to implement standards for acquisition and interpretation of PET/CT studies with other radiopharmaceuticals.

Keywords: Harmonization; Imaging; Positron emission tomography; Quantification; Radiopharmaceuticals; Standardization.

Publication types

  • Review

MeSH terms

  • Carbon Radioisotopes*
  • Choline
  • Humans
  • Medical Oncology / methods
  • Medical Oncology / standards*
  • Methionine
  • Neoplasms / diagnostic imaging*
  • Positron-Emission Tomography / methods
  • Positron-Emission Tomography / standards*
  • Radiopharmaceuticals*
  • Reference Standards
  • Tomography, X-Ray Computed / methods
  • Tomography, X-Ray Computed / standards*

Substances

  • Carbon Radioisotopes
  • Radiopharmaceuticals
  • Methionine
  • Choline