Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression

Leukemia. 2014 Dec;28(12):2395-8. doi: 10.1038/leu.2014.226. Epub 2014 Jul 18.

Authors

J Ojha¹, C Secreto², K Rabe², J Ayres-Silva³, R Tschumper², D V Dyke², S Slager², R Fonseca¹, T Shanafelt², N Kay², E Braggio¹

Affiliations

¹ Mayo Clinic, Scottsdale, AZ, USA.
² Mayo Clinic, Rochester, MN, USA.
³ National Institute of Cancer, Rio de Janeiro, Brazil.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

B-Lymphocytes / metabolism*
B-Lymphocytes / pathology
Clonal Evolution / genetics*
Disease Progression
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Lymphocytosis / diagnosis
Lymphocytosis / genetics*
Mutation*

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