A new twist on transcriptional bursting

David Levens; Daniel R Larson

doi:10.1016/j.cell.2014.06.042

A new twist on transcriptional bursting

Cell. 2014 Jul 17;158(2):241-242. doi: 10.1016/j.cell.2014.06.042.

Authors

David Levens¹, Daniel R Larson²

Affiliations

¹ Center for Cancer Research, National Cancer Institute, Bethesda, MD 20814, USA.
² Center for Cancer Research, National Cancer Institute, Bethesda, MD 20814, USA. Electronic address: [email protected].

Abstract

Transcriptional bursting has been observed across species and is one of the primary causes of variable gene expression in cells and tissue. In this issue, Chong et al. describe how DNA topology results in transcriptional bursting in E. coli.

Publication types

Comment

MeSH terms

Escherichia coli / genetics*
Transcription, Genetic*

Grants and funding

Z99 CA999999/Intramural NIH HHS/United States