Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin

Protein Cell. 2014;5(8):643-7. doi: 10.1007/s13238-014-0085-5.

Authors

Qianqian Chen¹, Juan Zhang, Kai Zhao, Wei Li, Qi Miao, Yang Sun, Xingyu Zhao, Taotao Wei, Fuyu Yang

Affiliation

¹ National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.

No abstract available

Publication types

Letter

MeSH terms

Apoptosis*
Calcineurin / metabolism*
Chymotrypsin / metabolism*
Humans
Lysosomes / enzymology*
Mitochondria / metabolism
Mitochondria / pathology*
Mitochondrial Dynamics
Neuroblastoma / metabolism
Neuroblastoma / pathology*

Substances

Calcineurin
Chymotrypsin