Lumbar discitis caused by Clostridium perfringens

J Clin Microbiol. 2014 Oct;52(10):3813-5. doi: 10.1128/JCM.00983-14. Epub 2014 Jul 23.

Abstract

We report here a rare case of chronic lumbar discitis caused by Clostridium perfringens in an elderly patient that was treated with a combination of β-lactams and clindamycin. Molecular analysis performed on the strain revealed an unusual toxin gene pattern.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Toxins / genetics
  • Clindamycin / therapeutic use
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / drug therapy
  • Clostridium Infections / microbiology
  • Clostridium Infections / pathology
  • Clostridium perfringens / genetics
  • Clostridium perfringens / isolation & purification*
  • Discitis / diagnosis*
  • Discitis / drug therapy
  • Discitis / microbiology
  • Discitis / pathology
  • Female
  • Genotype
  • Humans
  • Intervertebral Disc Degeneration / diagnosis*
  • Intervertebral Disc Degeneration / drug therapy
  • Intervertebral Disc Degeneration / microbiology
  • Intervertebral Disc Degeneration / pathology
  • Intervertebral Disc Displacement / diagnosis*
  • Intervertebral Disc Displacement / drug therapy
  • Intervertebral Disc Displacement / microbiology
  • Intervertebral Disc Displacement / pathology
  • Microbial Sensitivity Tests
  • Polymerase Chain Reaction
  • Spine / diagnostic imaging
  • Spine / pathology
  • Tomography, X-Ray Computed
  • beta-Lactams / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins
  • beta-Lactams
  • Clindamycin

Supplementary concepts

  • Intervertebral disc disease