Dengue virus transmission by blood stem cell donor after travel to Sri Lanka; Germany, 2013

Emerg Infect Dis. 2014 Aug;20(8):1366-9. doi: 10.3201/eid2008.140508.

Abstract

Three days after donation of peripheral blood stem cells to a recipient with acute myeloblastic leukemia, dengue virus was detected in the donor, who had recently traveled to Sri Lanka. Transmission to the recipient, who died 9 days after transplant, was confirmed.

Keywords: Dengue; Flaviviridae; Germany; PCR; RNA; Sri Lanka; arthropod; blood; donor; fatal; mosquito; stem cell; transplant; vectorborne; viruses.

Publication types

  • Case Reports

MeSH terms

  • Dengue / etiology
  • Dengue / transmission*
  • Dengue / virology
  • Dengue Virus / classification
  • Dengue Virus / genetics*
  • Genotype
  • Germany
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells*
  • Humans
  • Leukemia, Myeloid, Acute / complications
  • Leukemia, Myeloid, Acute / therapy
  • Male
  • Middle Aged
  • Phylogeny
  • Serogroup
  • Sri Lanka
  • Tissue Donors*
  • Travel*
  • Viral Envelope Proteins / genetics

Substances

  • Viral Envelope Proteins