Meta-analysis shows that infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications

Sabine E Bakhuizen; Timo R de Haan; Margreet J Teune; Aleid G van Wassenaer-Leemhuis; Jantien L van der Heyden; David P van der Ham; Ben Willem J Mol

doi:10.1111/apa.12764

Meta-analysis shows that infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications

Acta Paediatr. 2014 Dec;103(12):1211-8. doi: 10.1111/apa.12764. Epub 2014 Sep 7.

Authors

Sabine E Bakhuizen¹, Timo R de Haan, Margreet J Teune, Aleid G van Wassenaer-Leemhuis, Jantien L van der Heyden, David P van der Ham, Ben Willem J Mol

Affiliation

¹ Department of Obstetrics & Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands.

PMID: 25073543
DOI: 10.1111/apa.12764

Abstract

Infants suffering from neonatal sepsis face an increased risk of early death and long-term neurodevelopmental delay. This paper analyses and summarises the existing data on short-term and long-term outcomes of neonatal sepsis, based on 12 studies published between January 2000 and 1 April 2012 and covering 3669 neonates with sepsis.

Conclusion: Infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications such as brain damage and, or, neurodevelopmental delay.

Keywords: Morbidity; Mortality; Neonatal sepsis; Outcome; Prognosis.

Publication types

Meta-Analysis
Review

MeSH terms

Brain Damage, Chronic / epidemiology
Developmental Disabilities / epidemiology
Humans
Infant
Infant, Newborn
Sepsis / mortality*