Mice over-expressing human erythropoietin indicate that erythropoietin enhances expression of its receptor via up-regulated Gata1 and Tal1

Haematologica. 2014 Oct;99(10):e205-7. doi: 10.3324/haematol.2014.104844. Epub 2014 Aug 1.
No abstract available

Keywords: Gata1; Tal1; human erythropoietin; mice; overexpression; upregulation.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Basic Helix-Loop-Helix Transcription Factors / genetics*
  • Basic Helix-Loop-Helix Transcription Factors / metabolism
  • Erythropoietin / genetics*
  • Erythropoietin / metabolism
  • GATA1 Transcription Factor / genetics*
  • GATA1 Transcription Factor / metabolism
  • Gene Expression Regulation*
  • Humans
  • Mice
  • Mice, Transgenic
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins / metabolism
  • Receptors, Erythropoietin / genetics*
  • Receptors, Erythropoietin / metabolism
  • T-Cell Acute Lymphocytic Leukemia Protein 1

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • GATA1 Transcription Factor
  • Proto-Oncogene Proteins
  • Receptors, Erythropoietin
  • T-Cell Acute Lymphocytic Leukemia Protein 1
  • Tal1 protein, mouse
  • Erythropoietin