One-year MR angiographic and clinical follow-up after intracranial mechanical thrombectomy using a stent retriever device

AJNR Am J Neuroradiol. 2015 Jan;36(1):126-32. doi: 10.3174/ajnr.A4071. Epub 2014 Aug 14.

Abstract

Background and purpose: Little is known about the consequences of arterial wall damage that may be due to mechanical endovascular thrombectomy. Our aim was to perform 1-year MR angiographic and clinical follow-up of patients treated with mechanical endovascular thrombectomy using the Solitaire device.

Materials and methods: Patients with stroke treated between August 2010 and July 2012 were prospectively evaluated with a minimum follow-up of 1 year after mechanical endovascular thrombectomy. Angiographic follow-up was performed on a 3T MR imaging scanner and included intracranial artery TOF MRA and supra-aortic artery gadolinium-enhanced MRA. Images were assessed to detect arterial abnormalities (stenosis, occlusion, dilation) and were compared with the final post-mechanical endovascular thrombectomy run to differentiate delayed and pre-existing abnormalities. Clinical evaluation was performed with the mRS and the 36-Item Short-Form Health Survey questionnaire quality-of-life scale.

Results: Thirty-nine patients were angiographically assessed at the mean term of 19 ± 4 months. MRA showed intracranial artery abnormalities in 10 patients, including 5 delayed intracranial artery abnormalities in 4 patients (4 stenoses and 1 dilation), 4 cases of pre-existing intracranial artery stenosis, and 2 occlusions. Pre-existing etiologic cervical artery stenosis or occlusion was observed in 2 patients. All these patients remained asymptomatic during the follow-up period. A significant clinical improvement was observed at 1-year follow-up in comparison with 3-month follow-up (P < .0001), with a good outcome achieved in 62.5% of patients and an acceptable quality of life restored.

Conclusions: One-year follow-up identifies delayed asymptomatic arterial abnormalities in patients treated with the Solitaire device.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebral Angiography
  • Cerebral Arteries / diagnostic imaging*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Stroke / diagnostic imaging
  • Stroke / surgery*
  • Thrombectomy / adverse effects*
  • Thrombectomy / instrumentation*
  • Thrombectomy / methods
  • Treatment Outcome