Corneal collagen crosslinking failure in a patient with floppy eyelid syndrome

J Cataract Refract Surg. 2014 Sep;40(9):1558-60. doi: 10.1016/j.jcrs.2014.07.014.

Abstract

A 30-year-old man with bilateral floppy eyelid syndrome (more prominent in the left eye) and progressive keratoconus had corneal collagen crosslinking (CXL) in both eyes. No intraoperative or early postoperative complications were found. Topographic examination after CXL revealed a continuous increase in the keratometric values in the left eye in which the floppy eyelid syndrome was more prominent, indicating keratoconus progression (CXL failure). The fellow eye with the less prominent floppy eyelid syndrome remained stable during the follow-up period. Floppy eyelid syndrome could be a risk factor for CXL failure.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Collagen / metabolism*
  • Corneal Stroma / metabolism*
  • Corneal Topography
  • Cross-Linking Reagents*
  • Eyelid Diseases / complications*
  • Eyelid Diseases / physiopathology
  • Humans
  • Keratoconus / complications*
  • Keratoconus / drug therapy*
  • Keratoconus / physiopathology
  • Male
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use
  • Riboflavin / therapeutic use
  • Treatment Failure
  • Ultraviolet Rays

Substances

  • Cross-Linking Reagents
  • Photosensitizing Agents
  • Collagen
  • Riboflavin