[The prevalence and relevant factors of hyperglycemia in AIDS patients receiving antiretroviral therapy in a single center]

Zhonghua Nei Ke Za Zhi. 2014 Jun;53(6):446-9.
[Article in Chinese]

Abstract

Objective: To investigate the prevalence of hyperglycemia and its associated factors in AIDS patients receiving antiretroviral therapy (ART).

Methods: A cross-sectional survey was conducted to obtain the prevalence of hyperglycemia among AIDS patients in a single center. Univariate and multivariate non-conditional logistic regression analysis were used to determine influencing factors of hyperglycemia.

Results: A total of 504 AIDS patients participated in the survey, who have received ART for at least three months. The prevalence of hyperglycemia was 15.7%. Multivariate analysis showed that age (OR = 1.03, 95%CI 1.00-1.05), family history of diabetes (OR = 2.70, 95%CI 1.55-4.69), overweight (OR = 2.13, 95%CI 1.24-3.67), nadir CD4 cell counts 50-199 cells/µl (OR = 1.95, 95%CI 1.08-3.51) and less than 50 cells/µl (OR = 2.95, 95%CI 1.47-5.91) were relevant factors associated with hyperglycemia.

Conclusions: Blood glucose should be monitored regularly in AIDS patients receiving ART , especially among patients with old age, family history of diabetes, overweight and nadir CD4 T cell counts less than 200 cells/µl.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Acquired Immunodeficiency Syndrome / drug therapy*
  • CD4 Lymphocyte Count
  • CD4-Positive T-Lymphocytes
  • Cross-Sectional Studies
  • Diabetes Mellitus
  • Humans
  • Hyperglycemia / epidemiology*
  • Hyperglycemia / etiology
  • Logistic Models
  • Multivariate Analysis
  • Prevalence