Development and validation of a practical score to predict pain after excisional hemorrhoidectomy

Int J Colorectal Dis. 2014 Nov;29(11):1401-10. doi: 10.1007/s00384-014-1999-3. Epub 2014 Aug 26.

Abstract

Purpose: Excisional hemorrhoidectomy (EH) can be complicated by high early (EP) and prolonged pain (PP). This study aimed to determine predictors of high postoperative pain and to develop a risk score suitable to identify patient candidates to a more active analgesic treatment.

Methods: We collected data of patients undergoing EH between January 2005 and September 2012 (development group). Patient-, disease-, surgery-, and surgeon-related characteristics were gathered. Anxiety was evaluated by means of STAI-Y. EP was assessed at 1-day, while PP at 15-day follow-up by means of a 10-cm VAS (cutoff, EP ≥ 5; PP ≥ 3 cm). On the basis of the odds ratio from a logistic regression, independent risk factors were assigned a weighted integer. The sum comprised the risk score, which was validated on a prospective cohort of patients undergoing EH between September 2012 and January 2014.

Results: Five hundred fourteen patients were included in development group. Incidence of EP was 18.3 %, with 40.4 % developing PP. Younger age, male gender, advanced education, constipation, external component, anxious state and trait, and high anal resting tone were independent predictors of EP. Previous pain exerted a protective effect. Incomplete postoperative evacuation, advanced education level, high anal resting tone, and anxious trait were predictors of PP. In the development group, the risk of EP ranged between 1 % (low risk) and 21 % (high risk). Receiver operating curve (ROC) analysis of validation group (n = 130) confirmed the discriminatory power of this model (area under the ROC = 0.69).

Conclusion: The score can stratify the risk of EP following EH, identifying high-risk patient candidates to active analgesic administration or alternative surgical procedures.

MeSH terms

  • Adult
  • Age Factors
  • Anal Canal / physiology
  • Anxiety / complications
  • Constipation / complications
  • Educational Status
  • Female
  • Hemorrhoidectomy / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Overweight / complications
  • Pain, Postoperative / diagnosis*
  • Pressure
  • Retrospective Studies
  • Risk Assessment*
  • Sex Factors