Can LC-MS/MS and ligand-binding assays live in harmony for large-molecule bioanalysis?

Bioanalysis. 2014;6(13):1735-7. doi: 10.4155/bio.14.144.
No abstract available

Keywords: assay development; bioanalytics; biologic; free drug; large molecule; ligand-binding assay; mass spectrometry.

Publication types

  • Editorial

MeSH terms

  • Antibodies / immunology
  • Antibodies, Monoclonal / analysis
  • Antibodies, Monoclonal / pharmacokinetics
  • Chromatography, Affinity
  • Chromatography, High Pressure Liquid*
  • Ligands*
  • Macromolecular Substances / analysis*
  • Macromolecular Substances / pharmacokinetics
  • Tandem Mass Spectrometry*

Substances

  • Antibodies
  • Antibodies, Monoclonal
  • Ligands
  • Macromolecular Substances