Validation of LC-MS/MS bioanalytical methods for protein therapeutics

Bioanalysis. 2014;6(13):1739-42. doi: 10.4155/bio.14.125.
No abstract available

Keywords: PrD-LC–MS; enzymatic digestion; hybrid methods; protein digestion LC–MS/MS; quantitative protein LC–MS/MS; regulated biotherapeutic bioanalysis; validation.

Publication types

  • Editorial

MeSH terms

  • Chromatography, High Pressure Liquid* / standards
  • Enzymes / metabolism
  • Humans
  • Ligands
  • Proteins / analysis*
  • Proteins / metabolism
  • Proteins / standards
  • Reference Standards
  • Tandem Mass Spectrometry* / standards

Substances

  • Enzymes
  • Ligands
  • Proteins