Topiramate-Induced Acute Liver Failure in a Pediatric Patient: a Case Report and Review of Literature

J Pediatr Gastroenterol Nutr. 2016 Sep;63(3):e37-8. doi: 10.1097/MPG.0000000000000566.

Authors

Margaret Z Tsien¹, Jonathan Cordova, Asad Qadir, Lei Zhao, John Hart, Ruba Azzam

Affiliation

¹ *Department of Pediatrics †Section of Gastroenterology, Hepatology, and Nutrition, Comer Children's Hospital ‡Department of Internal Medicine §Department of Pathology, University of Chicago Medical Center ||University of Chicago Pritzker School of Medicine, Chicago, IL.

PMID: 25207478
DOI: 10.1097/MPG.0000000000000566

No abstract available

Publication types

Case Reports
Review

MeSH terms

Anticonvulsants / adverse effects*
Anticonvulsants / therapeutic use
Blood Coagulation Disorders / etiology
Blood Coagulation Disorders / prevention & control
Cerebral Palsy / complications
Chemical and Drug Induced Liver Injury / etiology*
Chemical and Drug Induced Liver Injury / pathology
Chemical and Drug Induced Liver Injury / physiopathology
Chemical and Drug Induced Liver Injury / therapy
Child
Combined Modality Therapy
Drug Monitoring
Epilepsy / complications
Epilepsy / drug therapy
Fructose / adverse effects
Fructose / analogs & derivatives*
Fructose / therapeutic use
Humans
Hyperammonemia / etiology
Hyperammonemia / prevention & control
Intellectual Disability / complications
Liver / drug effects*
Liver / pathology
Liver / physiopathology
Liver Failure, Acute / chemically induced*
Liver Failure, Acute / pathology
Liver Failure, Acute / physiopathology
Liver Failure, Acute / therapy
Male
Topiramate
Treatment Outcome

Substances

Anticonvulsants
Topiramate
Fructose