Radiation-induced cerebral aneurysm treated with endovascular coil embolization. A case report

Interv Neuroradiol. 2014 Jul-Aug;20(4):448-53. doi: 10.15274/INR-2014-10039. Epub 2014 Aug 28.

Abstract

Radiation-induced cerebral aneurysms are rare. We describe a case of radiation-induced cerebral aneurysm successfully treated with endovascular coil embolization. A 39-year-old man received 60 Gy of radiation to a pineal germinoma at eight years old. The left internal carotid artery (ICA) aneurysm which developed within the irradiated field and stenotic change in the left ICA due to radiation-induced vasculopathy were detected incidentally. Because these aneurysms show a high risk of rupture and mortality, and even small aneurysms are prone to rupture, any such suspected aneurysm should be treated with surgical or endovascular procedures. Endovascular treatment is probably useful if the aneurysm is inaccessible to direct surgery. Special attention must be paid to treatment because of stenotic changes in cerebral vessels within the irradiated field.

Keywords: endovascular coil embolization; germinoma; radiation therapy; radiation-induced aneurysm.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carotid Artery, Internal / diagnostic imaging
  • Carotid Artery, Internal / pathology
  • Cerebral Angiography / methods
  • Cerebral Infarction / etiology
  • Cerebral Infarction / pathology
  • Cerebral Infarction / therapy
  • Embolization, Therapeutic / methods*
  • Germinoma / radiotherapy*
  • Humans
  • Intracranial Aneurysm* / diagnostic imaging
  • Intracranial Aneurysm* / etiology
  • Intracranial Aneurysm* / therapy
  • Magnetic Resonance Imaging
  • Male
  • Pinealoma / radiotherapy*
  • Radiation Injuries / diagnostic imaging*
  • Treatment Outcome