Methaemoglobinaemia and haemolysis following pegloticase infusion for refractory gout in a patient with a falsely negative glucose-6-phosphate dehydrogenase deficiency result

Rheumatology (Oxford). 2014 Dec;53(12):2310-1. doi: 10.1093/rheumatology/keu346. Epub 2014 Sep 14.

Authors

Laura Geraldino-Pardilla¹, Diana Sung², Julia Z Xu², Maryam Shirazi², Eldad A Hod², Richard O Francis²

Affiliations

¹ Division of Rheumatology and Department of Pathology and Cell Biology, Columbia University, College of Physicians and Surgeons, New York, NY, USA. [email protected].
² Division of Rheumatology and Department of Pathology and Cell Biology, Columbia University, College of Physicians and Surgeons, New York, NY, USA.

PMID: 25224415
DOI: 10.1093/rheumatology/keu346

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
False Negative Reactions
Glucosephosphate Dehydrogenase Deficiency / diagnosis*
Gout / drug therapy*
Gout Suppressants / adverse effects*
Hemolysis / drug effects
Humans
Male
Methemoglobinemia / chemically induced*
Polyethylene Glycols / adverse effects*
Urate Oxidase / adverse effects*

Substances

Gout Suppressants
Polyethylene Glycols
Urate Oxidase
Pegloticase