A domino desulfurative coupling-acylation-hydration-Michael addition process for the synthesis of polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines
Chem Commun (Camb). 2014 Nov 14;50(88):13555-8.
doi: 10.1039/c4cc05090h.
1 College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, People's Republic of China. [email protected][email protected].
A novel method for the synthesis of the polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines through a domino desulfurative coupling-acylation-hydration and Michael addition sequence was established.