Long-term outcome and anaesthetic management for non-cardiac surgery after Fontan palliation: a single-centre retrospective analysis

Cardiol Young. 2015 Aug;25(6):1148-54. doi: 10.1017/S1047951114001814. Epub 2014 Sep 23.

Abstract

Objectives: The improved management of Fontan patients has resulted in good outcome. As such, these patients may necessitate care for non-cardiac surgery. We sought to determine the long-term outcome of our Fontan series palliated with the most recent surgical techniques. Our second objective was to report the incidence and the perioperative course after non-cardiac procedures. We reviewed the records of all patients with either a lateral tunnel or an extracardiac conduit Fontan between 1996 and 2008. Follow-up was recorded until June, 2013, including records regarding non-cardiac interventions.

Results: Overall, 58 patients were included. Of them, one patient underwent a takedown of his Fontan, and five patients died in the immediate postoperative course. The cumulative survival of the remaining 52 patients was 81%. There was no significant difference in survival between right and left ventricle morphologies (p=0.56), nor between both types of Fontan (p=0.9). Chronic arrhythmias (25%), fatigue/dyspnoea (40%), thrombotic complications (19%), and embolic events (10%) were among the most recurrent comorbidities. In total, 45 non-cardiac interventions were performed on 26 patients, with three bleeding complications and one death.

Conclusions: This study shows excellent long-term survival after both lateral tunnel and extracardiac conduit Fontan. The incidence of cardiovascular morbidity remains high, however. We also report a high number of non-cardiac interventions. Thorough understanding of the Fontan physiology is mandatory when non-cardiac anaesthesiologists are in charge of these patients.

Keywords: Fontan; long-term outcome; non-cardiac intervention.

MeSH terms

  • Aged
  • Anesthetics / therapeutic use*
  • Arrhythmias, Cardiac / etiology*
  • Child, Preschool
  • Comorbidity
  • Female
  • Fontan Procedure / adverse effects*
  • Heart Defects, Congenital / surgery*
  • Heart Ventricles / surgery
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Postoperative Complications*
  • Retrospective Studies
  • Survival Rate
  • Thromboembolism / etiology*
  • Treatment Outcome

Substances

  • Anesthetics