A rare cause of recurrent cerebral emboli despite oral anticoagulation

BMJ Case Rep. 2014 Sep 22:2014:bcr2014204223. doi: 10.1136/bcr-2014-204223.

Abstract

We report on a patient with a history of colon carcinoma and clinical presentation of recurrent cardiac emboli despite oral anticoagulation for atrial fibrillation. On delayed transoesophageal echocardiography, finally a left atrial myxoma was suspected. Surgery, however, revealed a left atrial metastatic tumour with histopathological features of a colon adenocarcinoma. Metastases of colorectal adenocarcinoma invading cardiac structures are rare. Isolated literature reports describe metastatic masses detected in the right atrium reflecting natural haematogenous spreading of cancer, but none in the left heart.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / pathology*
  • Anticoagulants / therapeutic use
  • Colorectal Neoplasms / complications
  • Colorectal Neoplasms / pathology*
  • Fatal Outcome
  • Heart Atria* / pathology
  • Heart Neoplasms / complications
  • Heart Neoplasms / secondary*
  • Humans
  • Intracranial Embolism / drug therapy
  • Intracranial Embolism / etiology*
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Recurrence
  • Treatment Failure

Substances

  • Anticoagulants