A case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever

J Ophthalmic Inflamm Infect. 2014 Sep 18:4:23. doi: 10.1186/s12348-014-0023-y. eCollection 2014.

Abstract

Background: Ocular and extraocular immune-mediated phenomena are known to occur following febrile illness. Vasculitis, retinitis and neurosensory detachment are not well-recognized sequelae of typhoid fever.

Findings: We report a case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever. A 27-year-old female presented with decreased vision in right eye with history of typhoid fever (treated adequately 6 weeks prior). Her best corrected visual acuity in right eye was 20/125, N36. Fundus showed a patch of vasculitis and retinitis superior to the disc associated with macular neurosensory detachment and disc pallor. With oral steroids, the inflammation resolved and visual acuity improved to 20/20 at 6 weeks.

Conclusions: Immune-mediated vasculitis and retinitis following typhoid fever may respond well to systemic steroids.

Keywords: Immune-mediated retinitis; Neuroretinitis; Post fever retinitis; Post typhoid retinitis.