Evaluation of the Xpert Flu rapid PCR assay in high-risk emergency department patients

J Clin Microbiol. 2014 Dec;52(12):4353-5. doi: 10.1128/JCM.02343-14. Epub 2014 Sep 24.

Abstract

We prospectively evaluated the performance of Cepheid's GeneXpert Xpert Flu assay in a target population of 281 adults presenting to the emergency department with an acute respiratory illness who met Centers for Disease Control and Prevention (CDC) criteria for recommended antiviral treatment. Compared with the Prodesse ProFlu+ assay, Xpert Flu had an overall sensitivity of 95.3% and specificity of 99.2%.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Emergency Medical Services / methods*
  • Emergency Service, Hospital
  • Female
  • Humans
  • Influenza, Human / diagnosis*
  • Male
  • Middle Aged
  • Molecular Diagnostic Techniques / methods*
  • Orthomyxoviridae / genetics
  • Orthomyxoviridae / isolation & purification*
  • Polymerase Chain Reaction / methods*
  • Prospective Studies
  • Sensitivity and Specificity