[Changes of oscillatory potentials of electroretinogram after methanol intoxication in rats]

Fa Yi Xue Za Zhi. 2014 Jun;30(3):178-80.
[Article in Chinese]

Abstract

Objective: To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats.

Method: The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room.

Results: The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule delayed approximately 16% and 61%, respectively.

Conclusion: The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.

MeSH terms

  • Animals
  • Electroretinography*
  • Methanol / poisoning*
  • Rats
  • Retina / physiopathology*

Substances

  • Methanol