Are the risk factors associated with Staphylococcus aureus nasal carriage in patients the same than in healthy volunteers? Data from a cohort of patients scheduled for orthopedic material implantation

Am J Infect Control. 2014 Oct;42(10):1121-3. doi: 10.1016/j.ajic.2014.06.026.

Abstract

The risk factors for Staphylococcus aureus nasal carriage have been mainly defined in healthy volunteers. Using data from a large multicenter prospective clinical cohort of orthopedic surgical patients we showed that obesity (BMI > 30) and younger age were independent risk factors for persistent carriage. In the absence of recommendations for S aureus decolonization in orthopedic surgery, this study suggests that at least obese patients should be targeted to prevent surgical site infections.

Keywords: Carriage; Colonization; Nosocomial infection; S aureus; Surgical site infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carrier State / epidemiology*
  • Carrier State / microbiology
  • Carrier State / transmission*
  • Disease Transmission, Infectious*
  • Female
  • Healthy Volunteers
  • Humans
  • Male
  • Middle Aged
  • Patients
  • Prospective Studies
  • Risk Assessment
  • Risk Factors
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / transmission*
  • Staphylococcus aureus / isolation & purification*
  • Wound Infection / epidemiology*
  • Wound Infection / microbiology