Challenges in managing infections among pediatric cancer patients: Suboptimal national essential medicines lists for low and middle income countries

Pediatr Blood Cancer. 2015 Feb;62(2):204-207. doi: 10.1002/pbc.25273. Epub 2014 Oct 12.

Abstract

Infection management for pediatric cancer patients may be compromised in low and middle income countries (LMICs) if key antimicrobials are not included in national essential medicines lists. We screened national essential medicines lists for 81 LMICs, and assessed the frequency and corresponding 95% confidence limits (CL) of countries that included the 15 International Society of Paediatric Oncology-recommended antimicrobial agents. Only 19% (95% CL: 11%, 28%) of countries included all recommended antimicrobials in their national essential medicines lists. The selection of antimicrobial agents for national essential medicines lists in LMICs warrants attention from a pediatric cancer perspective. Pediatr Blood Cancer 2015;62:204-207. © 2014 Wiley Periodicals, Inc.

Keywords: antimicrobials; essential medicines; infections; low and middle income countries; pediatric cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / economics*
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / economics*
  • Antifungal Agents / therapeutic use
  • Antiviral Agents / economics*
  • Antiviral Agents / therapeutic use
  • Bacterial Infections / drug therapy*
  • Drugs, Essential / economics*
  • Humans
  • Mycoses / drug therapy*
  • Neoplasms / therapy
  • Socioeconomic Factors
  • Virus Diseases / drug therapy*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Antiviral Agents
  • Drugs, Essential