Double solitaire mechanical thrombectomy in acute stroke: effective rescue strategy for refractory artery occlusions?

AJNR Am J Neuroradiol. 2015 Mar;36(3):552-6. doi: 10.3174/ajnr.A4133. Epub 2014 Oct 16.

Abstract

Background and purpose: Mechanical thrombectomy by using a single stent retriever system has demonstrated high efficacy for recanalization of large-artery occlusions in acute stroke. We aimed to evaluate the feasibility, safety, and efficacy of a novel double Solitaire stent retriever technique as an escalating treatment for occlusions that are refractory to first-line single stent retriever mechanical thrombectomy.

Materials and methods: All patients treated with the double stent retriever technique by using the Solitaire system were retrospectively selected from 2 large neurointerventional centers. Time to recanalization, angiographic (TICI) and clinical outcomes (mRS), and complications were assessed.

Results: Ten patients (median NIHSS score, 16; mean age, 70 years) with MCA M1 segment (n = 5) and terminal ICA (n = 5 including 2 ICA tandem) occlusions were included. Prior single stent retriever mechanical thrombectomy had been performed in 9 patients (median number of passes, 3). Median time to recanalization was 60 minutes (interquartile range, 45-87 minutes). Procedure-related complications occurred in 1 patient; overall mortality was 20%. Recanalization of the target vessel (TICI 2b/3) was achieved in 80%. Good clinical outcome (mRS 0-2) was 50%.

Conclusions: In this preliminary feasibility study, the double Solitaire stent retriever technique proved to be an effective method for recanalization of anterior circulation large-artery occlusions refractory to standard stent retriever mechanical thrombectomy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Arterial Occlusive Diseases / complications
  • Arterial Occlusive Diseases / surgery*
  • Cerebrovascular Disorders / complications
  • Cerebrovascular Disorders / surgery
  • Feasibility Studies
  • Female
  • Humans
  • Infarction, Middle Cerebral Artery / surgery
  • Male
  • Middle Aged
  • Retrospective Studies
  • Stents / adverse effects
  • Stroke / etiology
  • Stroke / surgery*
  • Thrombectomy / methods*
  • Treatment Outcome