In the reconstruction of extensive bone defects of the facial skeleton, bone grafts are taken for granted even though the handling and stress such grafts are subjected to do not always guarantee the functional and aesthetic result. The use of a special kind of prosthesis (osteo-mesh) consisting of the synthesis of two biocompatible substances (polyurethane and dacron) with bone graft, preferably iliac spongiosa, is suggested by the preliminary experience of the Authors, as a good solution for the achievement of a satisfactory result.