Spatio-temporal modelling of disease incidence with missing covariate values

Epidemiol Infect. 2015 Jun;143(8):1777-88. doi: 10.1017/S0950268814002854. Epub 2014 Oct 23.

Abstract

The search for an association between disease incidence and possible risk factors using surveillance data needs to account for possible spatial and temporal correlations in underlying risk. This can be especially difficult if there are missing values for some important covariates. We present a case study to show how this problem can be overcome in a Bayesian analysis framework by adding to the usual spatio-temporal model a component for modelling the missing data.

Keywords: risk factor.

MeSH terms

  • Bayes Theorem
  • Campylobacter Infections / epidemiology*
  • Cryptosporidiosis / epidemiology*
  • Humans
  • Incidence
  • Models, Statistical*
  • New Zealand / epidemiology
  • Rain*
  • Risk Factors
  • Spatio-Temporal Analysis*
  • Water Supply / statistics & numerical data*