Vaccine-induced waning of Haemophilus influenzae empyema and meningitis, Angola

Emerg Infect Dis. 2014 Nov;20(11):1887-90. doi: 10.3201/eid2011.140400.

Abstract

In Angola during 2003-2012, we detected Haemophilus influenzae in 18% of 2,634 and 26% of 2,996 bacteriologically positive pleural or cerebrospinal fluid samples, respectively, from children. After vaccination launch in 2006, H. influenzae empyema declined by 83% and meningitis by 86%. Severe H. influenzae pneumonia and meningitis are preventable by vaccination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Angola / epidemiology
  • Child
  • Child, Preschool
  • Empyema / epidemiology*
  • Empyema / microbiology
  • Haemophilus Vaccines / administration & dosage
  • Haemophilus Vaccines / immunology*
  • Haemophilus influenzae*
  • Humans
  • Infant
  • Meningitis, Haemophilus / epidemiology*
  • Meningitis, Haemophilus / microbiology
  • Population Surveillance
  • Prospective Studies
  • Vaccination

Substances

  • Haemophilus Vaccines