Macular toxicity following brilliant blue G-assisted macular hole surgery - a report of three cases

Nepal J Ophthalmol. 2014 Jan;6(11):98-101. doi: 10.3126/nepjoph.v6i1.10779.

Abstract

Introduction: Brilliant blue G is a new dye used for staining the internal limiting membrane to ease its peeling in cases like a macular hole.

Cases: Three patients presented with full-thickness idiopathic macular hole. They underwent pars planavitrectomy, Brilliant Blue G (BBG) stained internal limiting membrane peeling and fluid gas exchange.

Observations: Postoperatively,the macular hole closed but foveal thinning and perifoveal hyperpigmentation presumably due to BBG toxicity were observed in all three patients. All of them had a subnormal final best corrected visual acuity.

Conclusion: This case series highlights the unusual occurrence of macular toxicity following brillantblue G-assisted macular hole surgery.