Case study to illustrate an approach for detecting contamination and impurities in pesticide formulations

J Agric Food Chem. 2014 Nov 26;62(47):11347-52. doi: 10.1021/jf504729g. Epub 2014 Nov 12.

Abstract

Counterfeit pesticides threaten public health, food trade, and the environment. The present work draws attention to the importance of regular monitoring of impurities in formulated pesticide products. General screening revealed the presence of carbaryl as a contaminant in a copper oxychloride formulated product. In this paper, as a case study, a liquid chromatographic diode array-mass spectrometric method developed for general screening of pesticide products and quantitative determination of carbaryl together with its validation is presented. The proposed testing strategy is considered suitable for use as a general approach for testing organic contaminants and impurities in solid pesticide formulations.

Keywords: HPLC; LC-MS; carbaryl; copper oxychloride; counterfeit; impurities; monitoring; pesticides; quality control.

MeSH terms

  • Carbaryl / analysis
  • Chromatography, High Pressure Liquid
  • Gas Chromatography-Mass Spectrometry
  • Pesticide Residues / analysis*
  • Pesticides / analysis*
  • Reproducibility of Results
  • Risk Assessment

Substances

  • Pesticide Residues
  • Pesticides
  • Carbaryl