Quantitative electron density characterization of soft tissue substitute plastic materials using grating-based x-ray phase-contrast imaging

Rev Sci Instrum. 2014 Oct;85(10):103708. doi: 10.1063/1.4898052.

Abstract

Many scientific research areas rely on accurate electron density characterization of various materials. For instance in X-ray optics and radiation therapy, there is a need for a fast and reliable technique to quantitatively characterize samples for electron density. We present how a precise measurement of electron density can be performed using an X-ray phase-contrast grating interferometer in a radiographic mode of a homogenous sample in a controlled geometry. A batch of various plastic materials was characterized quantitatively and compared with calculated results. We found that the measured electron densities closely match theoretical values. The technique yields comparable results between a monochromatic and a polychromatic X-ray source. Measured electron densities can be further used to design dedicated X-ray phase contrast phantoms and the additional information on small angle scattering should be taken into account in order to exclude unsuitable materials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomimetic Materials / chemistry*
  • Electrons*
  • Interferometry
  • Optical Imaging / instrumentation*
  • Phantoms, Imaging
  • Plastics / chemistry*
  • Rotation
  • Synchrotrons
  • X-Rays

Substances

  • Plastics