Abstract
4-Alkyl- and 4-H-pyrazoles were sequentially metalated using TMPMgCl·LiCl, and their reaction with electrophiles afforded 3-aryl-4-alkyl-5-cyanopyrazoles.
MeSH terms
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Combinatorial Chemistry Techniques
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Hydrocarbons, Halogenated / chemistry*
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Magnesium / chemistry*
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Molecular Structure
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Nitriles / chemical synthesis*
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Nitriles / chemistry
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Organometallic Compounds / chemistry
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Pyrazoles / chemical synthesis*
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Pyrazoles / chemistry
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Stereoisomerism
Substances
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Hydrocarbons, Halogenated
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Nitriles
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Organometallic Compounds
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Pyrazoles
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TMPMgCl.LiCl
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Magnesium