Intense immunosuppression for the treatment of an immune reconstitution inflammatory syndrome-like exacerbation after natalizumab withdrawal: a case report

J Neurol. 2015 Jan;262(1):219-21. doi: 10.1007/s00415-014-7574-6. Epub 2014 Nov 20.

Authors

Maria Sepúlveda¹, Sara Llufriu, Yolanda Blanco, Nuria Solà-Valls, Delon La Puma, Joan Berenguer, Pablo Villoslada, Albert Saiz

Affiliation

¹ Center for Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain.

PMID: 25408366
DOI: 10.1007/s00415-014-7574-6

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Cyclophosphamide / administration & dosage
Cyclophosphamide / pharmacology
Female
Humans
Immune Reconstitution Inflammatory Syndrome / drug therapy
Immune Reconstitution Inflammatory Syndrome / etiology*
Immunologic Factors / administration & dosage*
Immunosuppression Therapy / methods*
Immunosuppressive Agents / administration & dosage*
Multiple Sclerosis, Relapsing-Remitting / drug therapy
Multiple Sclerosis, Relapsing-Remitting / physiopathology*
Natalizumab / administration & dosage
Rituximab / administration & dosage
Rituximab / pharmacology

Substances

Immunologic Factors
Immunosuppressive Agents
Natalizumab
Rituximab
Cyclophosphamide