Blood pressure percentiles in 22,051 German children and adolescents: The PEP Family Heart Study

Am J Hypertens. 2015 May;28(5):672-9. doi: 10.1093/ajh/hpu208. Epub 2014 Nov 19.

Abstract

Background: Strong associations between blood pressure (BP) and overweight raise the question whether overweight children (body mass index (BMI) ≥85th percentile) should be included in the normative database.

Methods: Using the LMS (Lamda-Mu-Sigma) method, we developed age-, gender-, and height-adjusted percentile curves for systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the 50th, 85th, 90th, 95th, and 97th percentiles in 22,051 German youths (18,917 normal-weight, 1,938 overweight, and 1,196 obese) aged 3-18 years from yearly cross-sectional surveys of the PEP Family Heart Study Nuremberg.

Results: Among children, we found no gender differences for BP and BMI. Male adolescents are taller and heavier. The mean prevalence of hypertension and obesity is 7.3% and 5.2% among children and 7.2% and 5.8% among adolescents, respectively. The prevalence of elevated BP increased substantially by weight groups achieving 24.4% in obese females and 21.9% in obese males with odds ratios of 5.9 (95% confidence interval (CI): 5.1-7.5) and 4.3 (95% CI: 3.5-5.2), respectively. The shapes of the 10 LMS-smoothed SBP and DBP percentile curves differ substantially between gender and weight group. The normal-weight percentiles are nearly identical with the overall growth charts, but separate percentiles for overweight and obese youths provide considerably higher values, such as 148/91 vs. 136/86 mm Hg for a 17-year-old male and 136/91 vs. 123/81 mm Hg for female, respectively, at the 90th percentile.

Conclusions: Because of substantially higher BP percentiles, separate databases for overweight and obese children and adolescents are strongly recommended.

Keywords: German youths; auscultatory blood pressure percentiles; blood pressure; hypertension..

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Blood Pressure / physiology*
  • Blood Pressure Determination*
  • Body Mass Index
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Germany / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Hypertension / etiology
  • Hypertension / physiopathology*
  • Male
  • Obesity / complications*
  • Obesity / epidemiology
  • Obesity / physiopathology
  • Prevalence
  • Retrospective Studies
  • Risk Factors