Low prevalence of HNF1A mutations after molecular screening of multiple MODY genes in 58 Italian families recruited in the pediatric or adult diabetes clinic from a single Italian hospital

Diabetes Care. 2014 Dec;37(12):e258-60. doi: 10.2337/dc14-1788.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Basic Helix-Loop-Helix Transcription Factors / genetics
  • Child
  • DNA Mutational Analysis
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / genetics*
  • Gene Frequency
  • Glucokinase / genetics
  • Hepatocyte Nuclear Factor 1-alpha / genetics*
  • Hepatocyte Nuclear Factor 1-beta / genetics
  • Hepatocyte Nuclear Factor 4 / genetics
  • Homeodomain Proteins / genetics
  • Hospitals
  • Humans
  • Italy / epidemiology
  • Mutation*
  • Pedigree
  • Polymorphism, Single Nucleotide
  • Prevalence
  • Trans-Activators / genetics

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • HNF1A protein, human
  • HNF1B protein, human
  • HNF4A protein, human
  • Hepatocyte Nuclear Factor 1-alpha
  • Hepatocyte Nuclear Factor 4
  • Homeodomain Proteins
  • NEUROD1 protein, human
  • Trans-Activators
  • pancreatic and duodenal homeobox 1 protein
  • Hepatocyte Nuclear Factor 1-beta
  • Glucokinase