Cost-effective analysis of unilateral vestibular weakness investigation

Otol Neurotol. 2015 Feb;36(2):277-81. doi: 10.1097/MAO.0000000000000649.

Abstract

Objectives: To evaluate the cost-effectiveness of obtaining a magnetic resonance imaging (MRI) in patients with abnormal electronystagmography (ENG) or videonystagmography (VNG) results.

Study design: Retrospective chart review.

Settings: Academic specialty center.

Patients: Patients presenting with vertigo between January 1, 2010, and August 30, 2013.

Methods: Patients who fit the following abnormal criteria were included in the study: unilateral caloric weakness (≥20%), abnormal ocular motor testing, and nystagmus on positional testing. Patients with abnormal findings who then underwent MRI with gadolinium were evaluated.

Results: Of the 1,996 charts reviewed, there were 1,358 patients who met the inclusion criteria. The average age of these patients was 62 years (12-94 yr). The male:female ratio was approximately 1:2. Of the 1,358 patients, 253 received an MRI with the following pathologies: four vestibular schwannomas, three subcortical/periventricular white matter changes suspicious for demyelinating disease, four acute cerebellar/posterior circulation infarct, two vertebral artery narrowing, one pseudomeningocele of internal auditory canal, and two white matter changes indicative of migraines. The positive detection rate on MRI was 5.5% based on MRI findings of treatable pathologies causing vertigo. Average cost of an MRI is $1,200, thereby making the average cost of identifying a patient with a positive MRI finding $15,180.

Conclusion: In our study, those patients with a positive MRI had a constellation of symptoms and findings (asymmetric sensorineural hearing loss, tinnitus, vertigo, and abnormal ENG/VNG). Cost-effectiveness can be improved by ordering an MRI only when clinical examination and VNG point toward a central pathology. Clinical examination and appropriate testing should be factored when considering the cost-effectiveness of obtaining an MRI in patients with abnormal ENG/VNG findings.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Cost-Benefit Analysis
  • Electronystagmography / economics*
  • Female
  • Hearing Loss, Sensorineural / diagnosis*
  • Hearing Loss, Sensorineural / economics
  • Humans
  • Magnetic Resonance Imaging / economics*
  • Male
  • Middle Aged
  • Neuroma, Acoustic / diagnosis*
  • Neuroma, Acoustic / economics
  • Retrospective Studies
  • Tinnitus / diagnosis*
  • Tinnitus / economics
  • Vertigo / diagnosis*
  • Vertigo / economics
  • Vertigo / etiology
  • Young Adult